Effects of lead exposure on survival, growth and development of forebrain in bufo regularis tadpoles

dc.contributor.authorNdimbumi, Joram
dc.date.accessioned2020-05-28T04:28:56Z
dc.date.available2020-05-28T04:28:56Z
dc.date.issued2008
dc.descriptionAvailable in print form, East Africana Collection, Dr. Wilbert Chagula Library, Class mark (THS EAF RA1231.L4N3754)en_US
dc.description.abstractThe effect of lead exposure on survival, growth and development of forebrain in Bufo regular is tadpoles fanuran species) were investigated. Tadpoles were exposed to 1.8, 3.5, 6, 10, and 15mg/l ambient lead for 96 hours. Mortality of tadpoles was recorded and the median lethal concentration (LC50) for lead was 5.1 mgPb/1 (96hrs). Forty eggs of Bufo regularis were exposed to 0.5, 1, 2, 4, 8 and 10 mg/1 of ambient lead in each test container for 7, 14, 21, 28 and 35 days. The bioaccumulation of lead in the body of tadpoles increased concomitantly with an increase in the ambient lead concentrations while the survival decreased with an increase of exposure concentrations and time. Tail malformation and swimming dysfunction were common in tadpoles exposed to 4, 8 and 10 mg/1. The histopathological study of the forebrain revealed poor development of the neural tube and delayed migration of neurons into the cortex of the forebrain. It can therefore be concluded that lead has detrimental effect on survival, growth and development of forebrain in Bufo regularis tadpoles. Hence discharge of waste containing lead in aquatic environment can have detrimental effects on early stages of amphibian developmenten_US
dc.identifier.citationNdimbumi, J (2008) Effects of lead exposure on survival, growth and development of forebrain in bufo regularis tadpoles, Master dissertation, University of Dar es Salaam. Dar es Salaam.en_US
dc.identifier.urihttp://41.86.178.5:8080/xmlui/handle/123456789/11606
dc.language.isoenen_US
dc.publisherUniversity of Dar es Salaamen_US
dc.subjectBufo regularis tadpolesen_US
dc.subjectGrowthen_US
dc.subjectForebrainen_US
dc.titleEffects of lead exposure on survival, growth and development of forebrain in bufo regularis tadpolesen_US
dc.typeThesisen_US
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